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Prior to the 15th Century: Infectious disease
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US weight Epidemic [www.publichealth.com.ng]This primitive form of inoculation was practiced in Africa and the Middle East too before
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public health ethics [www.publichealth.com.ng]as many as died before the age of 15, likely from dysentery, scarlet fever, whooping cough, influenza, smallpox, and pneumonia.
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There is perhaps no more terrible an example from history to illustrate the importance of antibodies in resisting infectious disease.
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